Are the laundry detergent sheets septic safe? January 26, 2023 15:38 Updated Yes, our sheets are septic safe. They’re even a favorite for many RVers who rely on small septic systems! Related articles Are your laundry detergent sheets compatible with HE machines? I don’t see any suds. Will it clean? Where are your Laundry Detergent Sheets made? What are the ingredients? I have a small washer that uses very little detergent. What should I do?